ROS-responsive drug delivery systems for biomedical applications

ROS‐responsive drug delivery systems

Reactive oxygen species (ROS) play an important role in signal transduction and metabolism. Over-produced ROS in cells or tissues, however, often leads to oxidation stress that has implications in a series of diseases including cancer, aging, atherosclerosis and inflammation. Driven by the need for on-demand drug delivery and fuelled by recent development of ROS-responsive materials and nanomed...

Smart polymers for responsive drug-delivery systems.

The rapid advancement of biomedical research has led to many creative applications for biocompatible polymers. As modern medicine discerns more mechanisms, both of physiology and of pathophysiology, the approach to healing is to mimic, or if possible, to recreate the physiology of healthy functioning. Thus, the area of smart polymers for responsive drug delivery has evolved. The developments fa...

particulate drug delivery systems in dermal applications

Multi-responsive hydrogels for drug delivery and tissue engineering applications.

Multi-responsive hydrogels, or 'intelligent' hydrogels that respond to more than one environmental stimulus, have demonstrated great utility as a regenerative biomaterial in recent years. They are structured biocompatible materials that provide specific and distinct responses to varied physiological or externally applied stimuli. As evidenced by a burgeoning number of investigators, multi-respo...

Recent advances in ceramic implants as drug delivery systems for biomedical applications

Research in the development of new bioceramics with local drug delivery capability for bone regeneration technologies is receiving great interest by the scientific biomedical community. Among bioceramics, silica-based ordered mesoporous materials are excellent candidates as bone implants due to two main reasons: first, the bioactive behavior of such materials in contact with simulated body flui...